SP Elixir (OPC) Private Limited

Hepbest 25mg Tablets contain Entecavir, an antiviral medication primarily used for the treatment of chronic hepatitis B infection.

Key Information:

• Active Ingredient: Entecavir.
• Class: Antiviral (specifically a nucleoside analogue).
• Mechanism of Action: Entecavir works by inhibiting the replication of the hepatitis B virus (HBV). It does this by interfering with the viral reverse transcriptase enzyme, which is crucial for the replication of the virus. By blocking this enzyme, Entecavir reduces the ability of the virus to reproduce and spread within the liver.

Common Uses:

• Chronic Hepatitis B: It is primarily prescribed to patients with chronic hepatitis B infection who have active viral replication and liver inflammation. It helps to reduce viral load, improve liver function, and reduce the risk of liver-related complications like cirrhosis and liver cancer.

Administration:

• Oral tablet typically taken once daily, with or without food.
• The dose may vary depending on whether the patient has been previously treated with other antiviral medications or if they have renal impairment (kidney problems). Your doctor will adjust the dose based on these factors.

Side Effects:

• Headache.
• Fatigue.
• Nausea or vomiting.
• Dizziness.
• Elevated liver enzymes (which could indicate liver injury or inflammation).
• Lactic acidosis (a rare but serious condition involving the buildup of lactic acid in the blood, leading to symptoms like muscle pain, breathing difficulty, and fatigue).
• Kidney problems: Monitoring of kidney function is necessary during treatment.

Precautions:

• Renal Impairment: In patients with kidney disease, the dose of Entecavir may need to be adjusted, and kidney function should be monitored closely.
• Liver Function: Regular liver function tests are recommended, as Entecavir can cause liver issues in some individuals.
• Pregnancy: It is important to inform the doctor if the patient is pregnant or planning to become pregnant, as the safety of Entecavir during pregnancy has not been fully established. It should only be used if the potential benefit outweighs the risks.
• Resistance: Long-term use of Entecavir can sometimes lead to drug resistance, especially if used in patients who have previously been treated with other hepatitis B medications. Regular monitoring of the patient's viral load is essential.

Hepbest 25mg Tablets are an effective treatment for chronic hepatitis B, helping to manage the infection and reduce liver damage. Regular follow-up with a healthcare provider is necessary to monitor the patient’s response to the medication and detect any potential side effects early.