Meropenem Injection

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Meropenem Injection lp 1000mg

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Strength1 gm
Pack Size20 ml
Pack TypeVial

Meropenem Injection LP 1000 mg is an antibiotic used to treat a variety of bacterial infections. It is a carbapenem class antibiotic, which is typically reserved for severe infections due to its broad spectrum of activity and effectiveness against many multi-drug resistant bacteria.

Key Information about Meropenem Injection LP 1000 mg:
  • Mechanism of action: Meropenem works by inhibiting the bacterial cell wall synthesis, which leads to the destruction of the bacteria. It is effective against a wide range of gram-positive and gram-negative bacteria, including some strains that are resistant to other antibiotics.

  • Indications: Meropenem is generally used to treat:

    • Intra-abdominal infections (e.g., peritonitis, appendicitis)
    • Pneumonia, including hospital-acquired and ventilator-associated pneumonia
    • Urinary tract infections (complicated ones)
    • Meningitis (bacterial infection of the membranes surrounding the brain and spinal cord)
    • Sepsis (infection in the blood)
    • Skin and soft tissue infections
  • Dosage: The typical dosage of Meropenem Injection is 1000 mg (1 gram) given intravenously. The exact dosage and duration will depend on the type and severity of the infection and the patient's overall health. It is usually administered every 8 hours, but your healthcare provider will guide the dosing schedule.

  • Administration: Meropenem is typically given as an intravenous (IV) injection or infusion in a hospital setting. It is not given orally. It should be administered slowly over 15-30 minutes (for IV infusion).

  • Side effects: Common side effects include:

    • Nausea, vomiting, or diarrhea
    • Rash
    • Abnormal liver function tests (increased liver enzymes)
    • Allergic reactions, including anaphylaxis (rare but serious)

    Serious side effects that require immediate medical attention include:

    • Seizures (especially in patients with kidney problems)
    • Severe allergic reactions (e.g., swelling, difficulty breathing)
  • Precautions:

    • Kidney function: Dosage adjustments are needed in patients with kidney problems, as the drug is excreted through the kidneys.
    • Allergies: Inform your doctor if you are allergic to beta-lactam antibiotics (e.g., penicillin or cephalosporins), as there may be cross-reactivity.
    • Pregnancy and breastfeeding: The use of Meropenem should be discussed with your doctor if you are pregnant or breastfeeding, as it should only be used when necessary.
  • Drug interactions: Meropenem may interact with other medications, such as valproic acid, which may reduce its effectiveness. It’s important to inform your doctor about all the medications you are taking, including over-the-counter drugs and supplements.

Monitoring:
  • Kidney function and liver function should be monitored regularly during treatment.
  • If you experience any unusual symptoms like dizziness, confusion, or difficulty breathing, contact your healthcare provider immediately.

Important: Always follow your healthcare provider's instructions for dosage and administration. Misuse or incorrect dosing can lead to antibiotic resistance, making the infection harder to treat in the future.

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