SP Elixir (OPC) Private Limited

Opdyta 100mg (Nivolumab) Injection contains nivolumab, an immunotherapy drug used to treat various types of cancer. Nivolumab is a monoclonal antibody that works by helping the body’s immune system recognize and attack cancer cells. It is part of a class of drugs called immune checkpoint inhibitors, specifically targeting the PD-1 (Programmed Death-1) receptor on T-cells, which are part of the immune system.

Nivolumab is approved for the treatment of several cancers, either alone or in combination with other treatments. Some of the common cancers treated with nivolumab include:

1. Non-Small Cell Lung Cancer (NSCLC): Nivolumab is used in advanced or metastatic non-small cell lung cancer, especially when other treatments have not been effective.
2. Melanoma: It is used to treat advanced melanoma, a type of skin cancer.
3. Renal Cell Carcinoma (RCC): Nivolumab is used to treat advanced kidney cancer.
4. Hodgkin Lymphoma: It can be used in the treatment of relapsed or refractory Hodgkin lymphoma, especially when other treatments have failed.
5. Head and Neck Squamous Cell Carcinoma (HNSCC): Nivolumab is used in cases of advanced head and neck cancer.
6. Urothelial Carcinoma: Used to treat bladder cancer, particularly in advanced stages.
7. Colorectal Cancer: Nivolumab can also be used in some cases of colorectal cancer, especially if the cancer is microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR).

Nivolumab works by blocking the PD-1 receptor on T-cells, which are immune cells that help recognize and destroy abnormal cells, including cancer cells. Under normal conditions, PD-1 acts as a checkpoint, preventing T-cells from attacking healthy cells. However, many cancer cells exploit this mechanism to avoid being attacked by the immune system. Nivolumab blocks PD-1, thereby "releasing the brakes" on the immune system, allowing T-cells to more effectively recognize and destroy cancer cells.

Nivolumab is administered through an intravenous (IV) infusion in a healthcare setting. The dosage and frequency depend on the type of cancer being treated, as well as the patient's overall health and response to treatment.

Opdyta 100 mg Injection contains Daptomycin, an antibiotic used to treat serious bacterial infections, especially those caused by gram-positive bacteria. It works by binding to the bacterial cell membrane and disrupting its function, leading to the death of the bacteria.

Common indications include:

• Complicated skin and soft tissue infections
• Bacteremia (bloodstream infections)
• Endocarditis (infection of the heart lining or valves)

Opdyta is typically used when other antibiotics are not effective, especially for infections resistant to other treatments like methicillin-resistant Staphylococcus aureus (MRSA). It is administered intravenously (IV) and requires monitoring for potential side effects, such as muscle pain, liver enzyme changes, and kidney function.

Cyramza (Ramucirumab) 500mg/50mL Injection is a monoclonal antibody used in the treatment of various types of cancer, particularly for patients with advanced or metastatic cancers.

• Active Ingredient: Ramucirumab.
• Mechanism of Action: Ramucirumab works by targeting and blocking vascular endothelial growth factor receptor 2 (VEGFR-2). This receptor is involved in the formation of blood vessels that supply nutrients to tumors. By inhibiting VEGFR-2, Cyramza helps restrict blood supply to the tumor, slowing its growth.

• Gastric Cancer: Used for advanced stomach or gastroesophageal junction cancer.
• Non-Small Cell Lung Cancer (NSCLC): In combination with other chemotherapy agents for advanced or metastatic NSCLC.
• Colorectal Cancer: For metastatic colorectal cancer, often combined with other treatments like chemotherapy.
• Hepatocellular Carcinoma (Liver Cancer): In combination with paclitaxel for advanced liver cancer.

• Intravenous (IV) infusion, typically given in a hospital or clinic setting.
• The typical dosing schedule varies depending on the type of cancer and the patient's overall health but is often administered every 2 weeks.

• High blood pressure (hypertension)
• Fatigue
• Diarrhea
• Decreased appetite
• Bleeding or bruising
• Headaches or dizziness
• Infection risk (due to potential effects on the immune system)

• Regular monitoring of blood pressure and liver function is necessary during treatment.
• Cyramza can cause significant bleeding, so patients with a history of bleeding disorders should use it cautiously.

This medication is typically prescribed by oncologists for specific types of cancer and should only be used under close medical supervision.

Renocel 4000 Injection contains recombinant human erythropoietin (rHuEPO), a synthetic version of the natural hormone erythropoietin. This hormone is produced by the kidneys and stimulates the bone marrow to produce red blood cells. Renocel 4000 is used to treat anemia associated with chronic kidney disease (CKD), particularly in patients undergoing dialysis, or to treat anemia caused by chemotherapy in cancer patients. The injection helps improve red blood cell production, reducing fatigue and improving oxygen delivery to tissues. It is typically administered by subcutaneous or intravenous injection, depending on the specific medical condition. Regular monitoring of hemoglobin levels is necessary during treatment.

Velpanat is a combination medication used to treat chronic hepatitis C. It contains two active ingredients:

1. Sofosbuvir (400mg): An antiviral drug that works by inhibiting the replication of the hepatitis C virus (HCV) inside the body.

2. Velpatasvir (100mg): Another antiviral agent that targets a different part of the hepatitis C virus, helping to prevent its replication.

This combination is commonly used for the treatment of chronic hepatitis C infection and is typically taken once a day, usually for a duration of 12 weeks, depending on the specific HCV genotype and the patient's health condition.

It is important to follow the dosing instructions given by your healthcare provider, as this treatment requires careful monitoring and adherence for optimal results.

If you have any specific questions about Velpanat, like its side effects or interactions with other drugs, feel free to ask!

Godonext 10ml Injection contains recombinant human erythropoietin (rHuEPO), a medication used to treat anemia (low red blood cell count) often caused by chronic kidney disease or as a result of chemotherapy. Erythropoietin stimulates the bone marrow to produce more red blood cells, helping to increase hemoglobin levels and improve oxygen delivery to tissues. The injection is typically administered subcutaneously or intravenously, depending on the condition being treated. Regular monitoring of blood counts is necessary during treatment to ensure effectiveness and to avoid potential side effects such as high blood pressure or blood clots.

Vorizol 200mg Tablet contains voriconazole, an antifungal medication used to treat serious fungal infections. Voriconazole belongs to the azole class of antifungals and works by inhibiting the enzyme lanosterol 14α-demethylase, which is involved in the production of ergosterol. Ergosterol is a crucial component of the fungal cell membrane, and its inhibition leads to the death of the fungal cells.

Vorizol is commonly prescribed for the treatment of:

• Invasive aspergillosis (caused by Aspergillus species)
• Candidemia (a Candida fungal infection in the bloodstream)
• Fungal infections in immunocompromised patients

The tablet is typically taken orally and is part of a treatment regimen that may also include other antifungal medications. Common side effects can include visual disturbances, liver enzyme abnormalities, headache, and nausea. Due to potential drug interactions and liver-related effects, regular monitoring is essential during treatment.

Patients should follow their healthcare provider's guidance carefully to minimize side effects and maximize the medication's effectiveness.

The amount of Tacrograf 2 Capsule you take and how often you take it depends on the type of transplant you have, your body weight, and what other medicines you are taking. Follow your doctor’s instructions carefully. You should take it on an empty stomach, at least 1 hour before or 2 hours after a meal. Take this medicine regularly to get the maximum benefit and keep taking it, even if you feel well. If you stop taking it, you may increase the chances of rejecting your transplanted organ.

Erbitux (Cetuximab) 5mg/mL is a monoclonal antibody used primarily to treat colorectal cancer (CRC) and head and neck cancer. It works by targeting and inhibiting the epidermal growth factor receptor (EGFR), which is often overexpressed in certain types of cancer cells. By blocking EGFR, Erbitux helps to prevent the cancer cells from growing and dividing, thus slowing or stopping the spread of cancer.

Erbitux is typically administered intravenously by a healthcare provider in a clinical or hospital setting. It is often used in combination with other chemotherapy drugs for better effectiveness, particularly in cases where the cancer is metastatic (has spread to other parts of the body).

Common side effects can include skin rashes, diarrhea, and infusion reactions, so monitoring during treatment is necessary. Additionally, it may be used in specific cases for non-small cell lung cancer (NSCLC) if the tumor has EGFR mutations.

Mederan 2mg Tablets contain melphalan, an alkylating chemotherapy agent used primarily to treat certain types of cancer, including multiple myeloma and ovarian cancer. It may also be used in some cases for breast cancer and non-Hodgkin lymphoma.

Melphalan works by damaging the DNA in cancer cells, which prevents them from replicating and causes them to die. This helps to slow or stop the growth of the cancer.

Mederan tablets are typically taken orally as part of a chemotherapy regimen and may be used alone or in combination with other chemotherapy drugs. It can cause side effects like bone marrow suppression (leading to low blood cell counts), nausea, vomiting, and fatigue, so close monitoring of blood counts and other side effects is essential during treatment.

Belustine 40mg Capsules contain lomustine, an alkylating chemotherapy agent used to treat various types of cancer, including brain tumors, Hodgkin's lymphoma, non-Hodgkin lymphoma, and melanoma. Lomustine works by damaging the DNA in cancer cells, preventing them from dividing and leading to their death.

It is typically used in combination with other chemotherapy agents as part of a cancer treatment regimen. Belustine is taken orally, and due to its potential to cause significant side effects, including bone marrow suppression (low blood cell counts), liver toxicity, and nausea, it requires regular monitoring of blood counts, liver function, and other health parameters during treatment.